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Study results are still limited due to inadequate diagnostic procedures. Internet-based interventions are a promising approach to prevention of mental disorders, enhancing existing methods. The meta-analysis conducted for depression severity revealed a posttreatment pooled effect size of standardized mean difference (SMD) =-0.35 (95% CI, -0.57 to -0.12) for short-term follow-up, SMD = -0.22 (95% CI, -0.37 to -0.07) for medium-term follow-up, and SMD = -0.14 (95% CI, -0.36 to 0.07) for long-term follow-up in favor of the Internet-based psychological interventions when compared with waitlist or care as usual. Eleven studies found significant improvements in symptom severity with small-to-medium effect sizes (d=0.11- d=0.76) in favor of the intervention groups. Three of them found significant differences in onset with a number needed to treat of 9.3-41.3. Only 5 studies reported incidence data assessed by means of standardized clinical interviews (eg, SCID). Two studies on posttraumatic stress disorder and 1 on panic disorder were also included.

Most studies examined prevention of eating disorders or depression or anxiety. Meta-analytical pooling of results took place if feasible.Īfter removing duplicates, 1169 studies were screened of which 17 were eligible for inclusion. Study quality was assessed using the Cochrane Risk of Bias Tool. Primary outcome was onset of mental disorder. Studies were selected according to defined eligibility criteria (adult population, Internet-based mental health intervention, including a control group, reporting onset or severity data, randomized controlled trial). The aim of this study was to systematically summarize the current state of research on Internet-based interventions for the prevention of mental disorders to give a comprehensive overview of this fast-growing field.Ī systematic database search was conducted (CENTRAL, Medline, PsycINFO). The Internet as a medium appears to be an opportunity for scaling up preventive interventions to a population level. However, they can be effectively reduced through prevention measures. Mental disorders are highly prevalent and associated with considerable disease burden and personal and societal costs.